Mannosulfan
Clinical data
Other names[(2R,3S,4S,5R)-3,4-dihydroxy-2,5,6-tris(methylsulfonyloxy)hexyl] methanesulfonate
ATC code
Identifiers
  • 1,2,5,6-Tetrakis-O-(methylsulfonyl)-D-mannitol
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC10H22O14S4
Molar mass494.51ย gยทmolโˆ’1
3D model (JSmol)
  • CS(=O)(=O)OC[C@H]([C@H]([C@@H]([C@@H](COS(=O)(=O)C)OS(=O)(=O)C)O)O)OS(=O)(=O)C
  • InChI=1S/C10H22O14S4/c1-25(13,14)21-5-7(23-27(3,17)18)9(11)10(12)8(24-28(4,19)20)6-22-26(2,15)16/h7-12H,5-6H2,1-4H3/t7-,8-,9-,10-/m1/s1
  • Key:UUVIQYKKKBJYJT-ZYUZMQFOSA-N
ย ย (verify)

Mannosulfan (INN) is an alkylating agent with the potential for the treatment of cancer. It is not approved by the United States FDA for cancer treatment. Research suggests it is less toxic than the alkyl sulfonate Busulfan.[1]

References

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  1. ^ Jeswani G, Paul SD (2017). "Recent Advances in the Delivery of Chemotherapeutic Agents". Nano- and Microscale Drug Delivery Systems. pp.ย 281โ€“98. doi:10.1016/B978-0-323-52727-9.00015-7. ISBNย 978-0-323-52727-9.
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๐Ÿ“š Artikel Terkait di Wikipedia

ATC code L01

L01AA10 Melphalan flufenamide L01AB01 Busulfan L01AB02 Treosulfan L01AB03 Mannosulfan L01AC01 Thiotepa L01AC02 Triaziquone L01AC03 Carboquone L01AD01 Carmustine

Lifileucel

(Semustine) Nimustine Ranimustine Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan Treosulfan) Aziridines: Carboquone Thiotepa Triaziquone Triethylenemelamine

FOLFIRI

(Semustine) Nimustine Ranimustine Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan Treosulfan) Aziridines: Carboquone Thiotepa Triaziquone Triethylenemelamine

Cisplatin

(Semustine) Nimustine Ranimustine Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan Treosulfan) Aziridines: Carboquone Thiotepa Triaziquone Triethylenemelamine

Fluorouracil

(Semustine) Nimustine Ranimustine Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan Treosulfan) Aziridines: Carboquone Thiotepa Triaziquone Triethylenemelamine

Talazoparib

(Semustine) Nimustine Ranimustine Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan Treosulfan) Aziridines: Carboquone Thiotepa Triaziquone Triethylenemelamine

Doxorubicin

(Semustine) Nimustine Ranimustine Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan Treosulfan) Aziridines: Carboquone Thiotepa Triaziquone Triethylenemelamine

Arsenic trioxide

(Semustine) Nimustine Ranimustine Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan Treosulfan) Aziridines: Carboquone Thiotepa Triaziquone Triethylenemelamine