Mitobronitol 📖 Wikipedia

Mitobronitol
	Stereo, skeletal formula of mitobronitol (2S,3S,4S,5S)-2,3,4,5-tetrol
Names
	Preferred IUPAC name 1,6-Dibromo-1,6-dideoxy-D-mannitol[citation needed]
	Systematic IUPAC name 1,6-Dibromohexane-2,3,4,5-tetrol
Identifiers
CAS Number	488-41-5 (2S,3S,4S,5S)-2,3,4,5-tetrol ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL161657 ; ChEMBL447629 ;
ChemSpider	4063 ; 5145112 (2S,3S,5R)-2,3,5-triol ; 5145112 (2R,3R,4R,5R)-2,3,4,5-tetrol ;
ECHA InfoCard	100.006.979
EC Number	207-676-8;
KEGG	D02020 ;
MeSH	Mitobronitol
PubChem CID	4208; 44119013 (2R,3R)-2,3-diol; 6713087 (2S,3S,5R)-2,3,5-triol; 2794952 (2R,3R,4R,5R)-2,3,4,5-tetrol; 656655 (2S,3S,4S,5S)-2,3,4,5-tetrol;
RTECS number	OP2800000 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol;
UNII	5UP30YED7N ;
CompTox Dashboard (EPA)	DTXSID3048158 DTXSID7022918, DTXSID3048158 ;
	InChI InChI=1S/C6H12Br2O4/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,9-12H,1-2H2 Key: VFKZTMPDYBFSTM-UHFFFAOYSA-N ;
	SMILES OC(CBr)C(O)C(O)C(O)CBr;
Properties
Chemical formula	C6H12Br2O4
Molar mass	307.966 g·mol−1
Appearance	Colourless crystals
log P	−0.226 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol
Acidity (pKa)	12.609 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol
Basicity (pKb)	1.388 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol
Pharmacology
ATC code	L01AX01 (WHO)
Related compounds
Related compounds	1,2-Dibromopropane; 1,3-Dibromopropane; 1,2,3-Tribromopropane;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Mitobronitol (1,6-dibromo-1,6-dideoxy-D-mannitol) is a brominated analog of mannitol. It is an anticancer drug that is also classified as an alkylating agent.^[2]

References

edit

^ "Mitolactol - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 25 March 2005. Identification. Retrieved 22 June 2012.
^ Mitobronitol, The Centre for Cancer Education

This antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by adding missing information.

[1] "Mitolactol - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 25 March 2005. Identification. Retrieved 22 June 2012.

[2] Mitobronitol, The Centre for Cancer Education

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[2]

Mitobronitol 📖 Wikipedia

References

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Names
Stereo, skeletal formula of mitobronitol (2S,3S,4S,5S)-2,3,4,5-tetrol
Preferred IUPAC name 1,6-Dibromo-1,6-dideoxy-D-mannitol^{[citation needed]}
Systematic IUPAC name 1,6-Dibromohexane-2,3,4,5-tetrol^[1]
Identifiers
CAS Number	488-41-5 (2S,3S,4S,5S)-2,3,4,5-tetrol^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL161657^Y ChEMBL447629^Y
ChemSpider	4063^Y 5145112 (2S,3S,5R)-2,3,5-triol^Y 5145112 (2R,3R,4R,5R)-2,3,4,5-tetrol^Y
ECHA InfoCard	100.006.979
EC Number	207-676-8
KEGG	D02020^Y
MeSH	Mitobronitol
PubChem CID	4208 44119013 (2R,3R)-2,3-diol 6713087 (2S,3S,5R)-2,3,5-triol 2794952 (2R,3R,4R,5R)-2,3,4,5-tetrol 656655 (2S,3S,4S,5S)-2,3,4,5-tetrol
RTECS number	OP2800000 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol
UNII	5UP30YED7N^Y
CompTox Dashboard (EPA)	DTXSID3048158 DTXSID7022918, DTXSID3048158
InChI InChI=1S/C6H12Br2O4/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,9-12H,1-2H2^Y Key: VFKZTMPDYBFSTM-UHFFFAOYSA-N^Y
SMILES OC(CBr)C(O)C(O)C(O)CBr
Properties
Chemical formula	C₆H₁₂Br₂O₄
Molar mass	307.966 g·mol⁻¹
Appearance	Colourless crystals
log P	−0.226 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol
Acidity (pK_a)	12.609 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol
Basicity (pK_b)	1.388 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol
Pharmacology
ATC code	L01AX01 (WHO)
Related compounds
Related compounds	1,2-Dibromopropane 1,3-Dibromopropane 1,2,3-Tribromopropane
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references