5-(Trifluoromethyl)-DMT
Clinical data
Other names5-TFM-DMT
Identifiers
  • N,N-dimethyl-5-(trifluoromethyl)-1H-Indole-3-ethanamine
CAS Number
PubChem CID
Chemical and physical data
FormulaC13H15F3N2
Molar mass256.272 g·mol−1
3D model (JSmol)
  • CN(C)CCC1=CNC2=CC=C(C(F)(F)F)C=C21
  • InChI=1S/C13H15F3N2/c1-18(2)6-5-9-8-17-12-4-3-10(7-11(9)12)13(14,15)16/h3-4,7-8,17H,5-6H2,1-2H3
  • Key:VOLQGCCSWTZFGQ-UHFFFAOYSA-N

5-TFM-DMT (5-(trifluoromethyl)-DMT, 5-CF3-DMT, 5-(trifluoromethyl)-N,N-dimethyltryptamine) is a putative psychedelic tryptamine derivative related to drugs such as 5-MeO-DMT, 5-Fluoro-DMT, and 5-TFMO-DMT. It acts as a partial agonist at the 5-HT2A receptor, with an EC50 of 185.7 nM and an efficacy of 28.7% (vs 5-HT), and a full agonist at 5-HT2C with an EC50 of 89.7 nM and an efficacy of 88.8%, and no significant activity at 5-HT2B.[1]

See also

edit

References

edit
  1. ^ US 2023/115167, Banister S, Jorgensen W, Jinlong T, "Compounds", published 29 June 2023, assigned to Psylo Pty Ltd. 


Stub icon

This hallucinogen-related article is a stub. You can help Wikipedia by adding missing information.

📚 Artikel Terkait di Wikipedia

5-Chloro-DMT

5-chloro-DMT include 5-chlorotryptamine, dimethyltryptamine (DMT), 5-fluoro-DMT, 5-bromo-DMT, 5-TFM-DMT, 6-fluoro-DMT, bretisilocin (5-fluoro-MET), 5-chloro-AMT

5-TFMO-DMT

antidepressant activity. Substituted tryptamine 5-MeO-DMT 5-EtO-DMT 5-Fluoro-DMT 5-Nitro-DMT 5-TFM-DMT 6-TFMO-DMT WO 2022/235927, Kruegel AC, "NOVEL TRYPTAMINES

Dimethyltryptamine

DMT derivatives include 1-methyl-DMT, lespedamine (1-MeO-DMT), 2-methyl-DMT, 4-methyl-DMT, 4-MeO-DMT, 4-fluoro-DMT, 5-methyl-DMT, 5-ethyl-DMT, 5-TFM-DMT

5-MeO-DMT

5-MeO-DMT, also known as 5-methoxy-N,N-dimethyltryptamine, as well as O-methylbufotenin or mebufotenin, is an atypical psychedelic drug, entheogen, and

5-Nitro-DMT

with modern techniques. Substituted tryptamine 5-Bromo-DMT 5-MeO-DMT 5-Nitrotryptamine 5-TFM-DMT 5-TFMO-DMT Shaw E, Woolley DW (April 1953). "The synthesis

5-Bromo-DMT

5-Bromo-DMT, or 5-Br-DMT, also known as 5-bromo-N,N-dimethyltryptamine or by informal names like sea DMT or SpongeBob DMT[dubious – discuss], is a psychedelic

Bufotenin

Bufotenin, also known as dimethylserotonin or as 5-hydroxy-N,N-dimethyltryptamine (5-HO-DMT), is a serotonergic psychedelic of the tryptamine family. It

5-Fluoro-DMT

related to dimethyltryptamine (DMT) and to other psychedelic tryptamines like 5-chloro-DMT and 5-bromo-DMT. 5-Fluoro-DMT was not included nor mentioned